They found 171 CpG sites representing 151 Entrez Gene IDs that were differentially methylated between ERα(+) and ERα(−) breast cancers with the following CpG sites hypermethylated in ER+ tumors: STAT5A, WNT1, DAPK1, ALPL, IFNGR2, IGFBP7, ST6GAL1 and TMEFF1. The gene discussed is ESR1; the disease is breast cancer.