The frequencies of the three genotypes of the TP53 gene polymorphism at codon 72 among the 61 HCC cases were 4.9% (n = 3), 32.8% (n = 20) and 62.3% (n = 38) proline homozygous, heterozygous and arginine homozygous, respectively, and the corresponding figures among controls were 7.4% (n = 9), 34.4% (n = 42), and 58.2% (n = 71), respectively. Here, TP53 is linked to hepatocellular carcinoma.