Besides these, two glycolytic genes glucose transporter 1(GLUT1) and glucose transporter 2 (GLUT2) were upregulated by HIF-1α to 2.98 and 3.74 respectively, so we concluded that HIF-1α maybe upregulate the glycolysis reaction of SCLC. This evidence concerns the gene SLC2A1 and small cell lung carcinoma.