Lipohypertrophy is a frequent problem in young patients with type 1 diabetes, occurring in up to 50% of patients, it may be associated with poor glycaemic control, [1] Although a cause for these lesions is not known, the predisposing conditions may be trauma to the skin and subcutaneous tissue repeated over time in the presence of insulin [2]. This evidence concerns the gene INS and type 1 diabetes mellitus.