CD4 and infection: Choudhary et al. showed that a combination of the RT inhibitors emtricitabine, tenofovir disoproxil fumarate, and an experimental strand transfer inhibitor (L-870812) was able to both reduce viral load as well as to rescue from CD4+ T cell loss when administration was begun 10-20 days after intravenous infection of RAG-hu mice with JR-CSF (dose of virus not reported).