Further proteins that may play a role in the boosting of E. histolytica virulence under GS are proteins encoded by genes up-regulated in trophozoites isolated from hamster liver abscesses [33] such as the 20 kDa antigen (EHI_056490) and the lysine-rich proteins, KRiP1 (EHI_096350) and KRiP3 (EHI_110740) (Table 2 and [33]). The gene discussed is TRIM28; the disease is Liver abscess.