MGMT and glioblastoma: To our surprise, in the Kaplan-Meier survival curve of patients with primary GBM, univariate analysis indicated a lower p value in the comparison of <68% and ≥68% of LINE-1 methylation than in the comparison of <14% and ≥14% of MGMT promoter methylation (p = 0.010 and 0.015, Figure 6AB).