To confirm whether the apoptosis enhancing effects observed in Figure 3 are mediated by survivin inhibition on protein level, we examined the protein expressions in HCC cells treated with ABT-263 (1 μM), YM-155 (1 μM), or the combination of YM-155 (1 μM) and ABT-263 (1 μM). Here, BIRC5 is linked to hepatocellular carcinoma.