Despite their dense cellularity, fewer and smaller vessels were detected in these tumours (Fig. 3C2 and 3D2), where quantification of the vascular area fraction and vascular density proved that the NG2 shRNA treated tumours were significantly less vascularised (microvascular area fraction, p = 0.006 t-test, and microvascular density, p = 0.010 t-test, respectively, Fig. 3E, left and right panels, respectively), compared to the NG2 positive tumours. Here, CSPG4 is linked to neoplasm.