In ovarian cancer, there was a strong association between exon 20 PIK3CA and KRAS mutations (3/4 [75%] in KRAS mutant vs. 2/40 [5%] in wtKRAS; p = 0.003), while the association between exon 9 PIK3CA and KRAS mutations did not reach statistical significance (1/2 [50%] in KRAS mutant vs. 1/39 [3%] in wtKRAS; p = 0.1). This evidence concerns the gene PIK3CA and ovarian cancer.