Lastly, four of the nine TPOA associated SNPs (in SH2B3, CTLA4, BACH2 and UBASH3A) have also been associated with celiac disease [33] (but not the SNPs in RASGRP1, STAT4, PTPN22, IL2[20] and FCRL3[33]). Here, SH2B3 is linked to celiac disease.