EGFR and head and neck squamous cell carcinoma: EGFR promotes growth and survival through several oncogenic signalling pathways, and its overexpression in SCCHN correlates with poor prognosis, short disease-free survival, and increased locoregional recurrence (Ang et al, 2002; Eriksen et al, 2004; Hitt et al, 2005; Chung et al, 2006), and makes it an attractive therapeutic target for therapy (Bonner et al, 2002; Johns et al, 2003; Harari et al, 2007).