Use of EPO pre transplant is associated with better 5 year graft survival and reduce frequency of rejection [39], concerning the level of EPO in the post transplant period, in a study compared two groups (anaemic & non-anaemic) of renal transplant recipients with normal renal functions, EPO deficiency and resistance play a causative role for PTA [40], however in other study no relation was found between administration of the EPO and anaemia, the same result favoring use of EPO only on high risk patients [41]. Here, EPO is linked to anemia (phenotype).