Stimulation of 1 million total cells from tumor digested products with an equivalent number of irradiated aAPC loaded with anti-CD3/28 antibodies in media supplemented with IL-2 yielded on average a 75-fold numerical expansion of total cells after 11 days, which was substantially higher than that achieved by IL-2 culture alone (mean of 5.6-fold; Figure 5b). This evidence concerns the gene IL2 and neoplasm.