Given the overall low prevalence of HIV infection among those tested in BC (approximately 0.2%) and the fact that pooled NAT screening of HIV seronegative samples is not performed, the 6.2% yield of AHI is quite high compared with the 3.95% yield from the North Carolina population-based screening programme, which used pooled NAT to test first-generation EIA negative specimens [12]. This evidence concerns the gene BRD2 and HIV infectious disease.