Thus, in the breast cancer cell lines, AAV2 regulation of c-Myc activation could potentially mediate simultaneous growth stimulatory (G1/S, S and G2 phase targeting), and growth inhibitory (apoptosis/necrosis associated DNA damage) signals which could represent a central unifying mechanism of AAV2 induced cell death in multiple breast cancer types. The gene discussed is MYC; the disease is breast carcinoma.