ARX and infantile spasms: Two recently published mouse models of ARX loss of function mutations, one of which specifically disrupted it in GABAergic interneurons destined to migrate to the neocortex, have recapitulated several phenotypes of infantile spasms and associated phenotype (cognitive, behavioral deficits and epileptogenesis) emphasizing the importance of deficient GABA inhibition for their pathogenesis [64, 66].