CCL2 and early-onset autosomal dominant Alzheimer disease: For example, cerebrospinal fluid levels of IL-8, IP10 and MCP-1 [16], and plasma levels of eotaxin [17] and MCP-1 [18], were independently shown to be increased in Alzheimer’s disease and recentlyIP10 and eotaxin was suggested markers for age-related macular degeneration [19].