CASP3 and cancer: However, studies from our group also demonstrated that this plant is an extremely powerful inducer of cancer cell death and possibly the bioactive compound from I. suffruticosa could act binding many molecular targets inside the cell activating alternative apoptotic pathways or inducing mitotic catastrophe which indicates a form of cell death that is caused by aberrant mitosis by caspase 3 activation and oligonucleosomal DNA degradation [24].