Established guidelines in Europe for diagnosing coeliac disease involves firstly analyses of serological markers (antihuman tissue transglutaminase of isotype IgA), and, if these are elevated, a secondary evaluation of a small bowel mucosal specimen to reveal enteropathy, followed by normalisation of serological markers and symptoms consequent upon a strict gluten-free diet. This evidence concerns the gene TGM2 and Abnormal intestine morphology.