SCN2A and scrapie: The HPLC-MS data also allowed us to show that, compared to normal brains, CE/CT percentages significantly increased (p = 0.029) in brains of the scrapie-affected mouse group (from 9.2% to 12.3%), while they did not vary in N2a and ScN2a cells (27.0% vs. 26.8%, respectively) (tables 1 and 2).