WNT3 and Parkinson disease: Our data support the possibility that a variant(s) in the NSF and WNT3 may contribute to PD, independent of MAPT. This association was replicated in the NINDS dataset, but not in the CIDR/pankratz et al 2009 dataset because the CIDR/Pankratz et al 2009 dataset lacked the associated SNP in WNT3. Taken together and based on the function of these genes, there is suggestive evidence that NSF and WNT3 are candidate genes that need to be further studied.