Furthermore, a follow up of Vhlfloxed-UBC-Cre-ERT2 mice revealed that they started to show anemia after a longer time period upon Vhl gene inactivation (hematocrit %: 42.62±2.22 in Vhlfloxed versus 33.2±3.8 in Vhlfloxed-UBC-Cre-ERT2; n = 7, p = 0.041). Here, VHL is linked to anemia (phenotype).