With the use of these well recognized markers, it appeared that ATC tissue harbored only three types of cells: NOX2+ P22phox+ CD163+ CD68+ CD34− macrophages; NOX2− P22phox− CD163− CD68− CD34− cancer cells and NOX2− CD163− CD68− CD34+ blood vessel endothelium. The gene discussed is CYBB; the disease is cancer.