OGFR and familial pancreatic carcinoma: Among others, these latter genes consisted of gained genes such as the PSCA gene, a plausible PDAC tumor marker associated with pancreatic cancer progression[19]–[22], the TNFRSF6B gene (a member of the tumor necrosis factor receptor family) which is amplificated in many tumors [23]–[26] and whose overexpression blocks growth inhibition signals in PDAC[27], and the NTSR1 and OGFR genes, involved in cancer progression[28]–[30], modulation of angiogenesis[31] and regulation of cell proliferation[32].