As both allergen sensitization [11] and obesity [12–14] have been shown to contribute to asthma development in children, we investigated the relevance of allergen-specific sensitization and body mass index (BMI) to asthma among schoolchildren in Kumasi, and whether the associations of asthma and EIB with specific IgE (sIgE) antibody responses and BMI differs between urban affluent, urban poor and suburban/rural children. Here, IGHE is linked to asthma.