Recent studies have also highlighted key biomarkers for MM, including soluble mesothelin-related peptide/megakaryocyte potentiating factor (both encoded by the same gene) (Cristaudo et al. 2007; Pass et al. 2008; Scherpereel and Lee 2007), osteopontin (Scherpereel and Lee 2007), and MN/CA9 (Li et al. 2007). Here, SPP1 is linked to Miyoshi myopathy.