POMC and neoplasm: ENSAT recommends performing the following tests to determine the secretory activity of the tumor: levels of fasting blood glucose, serum potassium, cortisol, ACTH, 24-hour urinary free cortisol, fasting serum cortisol at 8 AM following a 1 mg dose of dexamethasone at bedtime, adrenal androgens (dehydroepiandrosterone sulfate, androstenedione, testosterone, and 17-OH progesterone), and serum estradiol in men and post-menopausal women [7].