PLAT and cardioembolic stroke: Importantly, a graded response in neurological improvement at 24 hours and long-term outcome was observed in relation to the speed of clot lysis during tPA administration and consequently, favourable outcome at 3 months was higher (59% versus 40% versus 11%) and mortality rate was lower (13% versus 19% versus 41%) in cardioembolic stroke patients in comparison with undetermined and large-vessel disease stroke, respectively [61].