More recently, studies in the Han Chinese population have involved the HLA-B locus with very strong drug-specific associations: the HLA-B*1502 allele was found in all carbamazepine-induced SJS/TEN patients [14] and the HLA-B*5801 in all allopurinol-induced SJS/TEN patients [15]. The gene discussed is HLA-B; the disease is toxic epidermal necrolysis.