IFNG and tuberculosis: Compared to subjects with baseline IFN-γ responses to WCL alone, subjects responding to both WCL and ESAT-6 exhibited a trend toward enhanced protection from HIV-associated TB compared (HR 0.43, 95% CI 0.18−1.06, P = 0.069), whereas subjects responding to both WCL and Ag85 did not (HR 0.85, 95% CI 0.35−2.05, P = 0.715).