With respect to the tumour stroma, there was higher expression in the stroma of ES patients compared with PS patients for NM-CD163 (45.9 versus 22.2 cells/mm2) (p = 0.04) and lower expression in the stroma of ES compared to PS patients for NM-iNOS (6.4 versus 17.7 cells/mm2, p = 0.002) and NM-MRP 8/14 (3.9 versus 9.8 cells/mm2, p = 0.01) (Figs. 3A and B). This evidence concerns the gene CD163 and neoplasm.