The Pex26-Pex6-Pex1 complex was involved in peroxisome biogenesis disorders (PBDs), which included the Zellweger syndrome spectrum (PBD-ZSD) and rhizomelic chondrodysplasia punctata type 1 (RCDP1). The gene discussed is PEX26; the disease is rhizomelic chondrodysplasia punctata type 1.