Since some immune cell types in the periphery or CNS, such as microglial cells or CD4+ T cells, have been suggested to be associated with pathogenesis of neuroinflammatory disorders, including autism [23], [41]–[44], we evaluated proportions and actual numbers of major immune cell types in the spleen, mesenteric lymph nodes, peripheral blood, and brain of BTBR mice, and compared the levels with those for B6 mice (Tables 3 & 4, Fig. 6). Here, CD4 is linked to autism.