TNF and neoplasm: In conclusion our data evidenced that (a) these antioxidants inhibited the tumor cell growth in dose and time dependent way, (b) they induced the TNF-α, IL-1β and IL-8 decrease and the IL-10 increase promoting tumor regression and (c) new molecule 2-S-lipoyl-caffeic acid had a cytotoxic effects similar to caffeic acid.