Several receptor (EGFR, IGFR1, FGFR1...) and non-receptor (Abl) kinases have been selected, as well as serine/threonine/lipid kinases (AurA, Akt, CDKs, MAPKs...) implicated in main cancer pathways: cell cycle regulation, signal transduction, angiogenesis regulation among them. The gene discussed is AKT1; the disease is cancer.