EGFR and non-small cell lung carcinoma: Gefitinib (ZD1839, Iressa; AstraZeneca) and erlotinib (Tarceva, OSI-774; OSI Pharmaceuticals) are orally active epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) used for the treatment of non-small cell lung cancer (NSCLC) patients [1].