Treatments are essentially aimed at controlling hyperglycemia, which includes insulin (sulphonylureas, meglitinides, glucagon-like peptide (GLP) analogs, etc.)and insulin sensitizers which reduce hepatic glucose generation (metformin) or enhance peripheral glucose uptake by muscle and adipose tissue (metformin, thiazolidinediones, etc.), but no drug in vogue intrinsically exerts both the effects [4]. Here, INS is linked to Hyperglycemia.