CXCR4 and cancer: The chemokine receptor subtype CXCR4 is an attractive target for cancer diagnosis and treatment as it is overexpressed on more than 70 % of human solid tumors, including mammary cancer, prostate cancer, B-cell lymphoma, neuroblastoma, melanoma, cervical adenocarcinoma, and glioma, among others.[9] Moreover, it is involved in three fundamental aspects of cancer: primary tumor growth, cancer cell migration, and establishment of metastatic sites; and therefore, it can be considered an ideal target.