After including overweight/obesity into the model, the odds of having hypertension were greater than two times higher in men if they were overweight/obese (OR 2.41, 95% CI 1.88–3.09) while the relationship between CD4 count and hypertension had a smaller estimate of effect and was not statistically significant (OR 1.23, 95% CI 0.95–1.58). This evidence concerns the gene CD4 and obesity due to melanocortin 4 receptor deficiency.