RXRA and central nervous system cancer: When analyzed at individual time points, we found that G-protein coupled receptor signaling and PPARα/RXRα activation were significant at 1 h; glioma invasiveness signaling and taurine and hypotaurine metabolism were significant at 24 h; ERK/MAPK signaling was significant at 1 and 24 h; and IL-1 signaling was significant at 3 and 6 h.