MME and infection: Decreased CD10 expression has been associated with increased susceptibility to infections, likely due to its role in neutrophil chemotaxis and coordination of the inflammatory response.22 This becomes clinically evident amongst neonates, patients with burns and those with systemic sepsis, all of which have been shown to have both reduced CD10 expression on their granulocytes, and a degree of immunosuppression.6 The clinical implications of the reduced CD10 expression noted in HIV-1 positive patients remain unknown.