Immune reconstitution after transplantation has been compared for Cb and allo-Bmt; Moretta et al. found that reconstitution was not only comparable between the two progenitor cell sources, but Cb recipients actually showed a higher number of B cells, with a better CD4+ T-cell recovery in unrelated Cb recipients, which the authors attributed to the decreased GvHD effect [71]. The gene discussed is CD4; the disease is graft versus host disease.