Positive correlations were observed between the intrahepatic expression levels of Foxp3 with the expression of Fas (P =  .014), FasL (P <  .001) and TRAIL (P =  .003) (Figure 2), Fas and TRAIL (P <  .001), and FasL and IFN-γ (P <  .001), irrespective of the cause of liver damage (viral, NAFLD, autoimmunity, MTX). This evidence concerns the gene FAS and metabolic dysfunction-associated steatotic liver disease.