KIAA1199 has been associated with cancer tissues: high KIAA1199 transcript levels were found in mortal but not immortal renal cell carcinoma cells (Michishita et al, 2006) whereas low KIAA1199 expression in gastric cancers was related to significant better outcome of the patients (Matsuzaki et al, 2009). The gene discussed is CEMIP; the disease is hereditary clear cell renal cell carcinoma.