It is well established that the anti-mycobacterial response at the TB disease site is strongly Th1 driven.3–6 We detected high IFN-γ levels in pleural fluid samples from TB patients (median 5050 pg/mL, IQR 465-10,875) and in pericardial fluid from TB pericarditis patients (median 1450 pg/mL, IQR 0-3326) (Figure 3A). The gene discussed is IFNG; the disease is tuberculosis.