PIK3C2A and rhabdomyolysis: The proportion of patients with rhabdomyolysis (CPK levels increase above five ULN) or increase of liver enzymes (aminotransferases increase above three ULN) did not differ between the discontinuation and continuation groups: 3 (14%) vs. 1 (3%), P = 0.15; and 6 (25%) vs. 7 (18%), P = 0.54, respectively.