Because FGF signaling in cancer has been associated with induction of angiogenesis and lymphocytic infiltration [21], the number of microvessels was determined and T-cell infiltrate was quantified in breast tumors from patients whose fibroblasts had relatively high (n = 11) or relatively low (n = 14) FGFR2 expression. This evidence concerns the gene FGFR2 and cancer.