Anti-HELZ antibody specificity was verified by RNA interference-mediated HELZ knock-down in HEK293 cells (stable clone 4–10) as well as by using the Hodgkin's lymphoma-derived cell line DEV that contains a 3-megabase homozygous deletion at 17q24.1–24.2, which includes, amongst others, HELZ [23]. This evidence concerns the gene HELZ and Hodgkins lymphoma.