In addition, the elevated level of the gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), was consistently found in cysts and the peritoneal fluid of patients with ovarian cancer or borderline ovarian tumors, compared to benign cysts or benign tumors [5], which has attracted considerable attention, along with the status (positive or negative) of the LH receptor (LHR), a member of the G protein-coupled receptor family, in the cancer. Here, PLOD1 is linked to cancer.